| Robot | LPS+LESS | ||
|---|---|---|---|
| Segmental | 26 | 13 | 39 |
| NxUx | 456 | 1531 | 1987 |
| LESS | 0 | 7 | 7 |
| 482 | 1551 | 2033 |
| Robot | LPS+LESS | ||
|---|---|---|---|
| N | 479 | 1545 | 2024 |
NA| level | 1 ROBOT | 2 LPS+LESS | p | test | SMD | |
|---|---|---|---|---|---|---|
| n | 479 | 1545 | ||||
| ECOG (%) | 0 無症狀 | 248 (51.8) | 609 (39.4) | <0.001 | 0.521 | |
| 1 有症狀,可步行對生活不影響 | 187 (39.0) | 536 (34.7) | ||||
| 2 躺在床上時間小於50% | 22 ( 4.6) | 83 ( 5.4) | ||||
| 3 躺在床上時間大於50% | 3 ( 0.6) | 9 ( 0.6) | ||||
| 4 完全臥床 | 0 ( 0.0) | 4 ( 0.3) | ||||
| NA | 19 ( 4.0) | 304 (19.7) | ||||
| 性別 (%) | 1 男 | 202 (42.2) | 636 (41.2) | 0.736 | 0.020 | |
| 2 女 | 277 (57.8) | 909 (58.8) | ||||
| BMI (%) | Normal | 228 (47.6) | 582 (37.7) | <0.001 | 0.321 | |
| Overweight | 133 (27.8) | 354 (22.9) | ||||
| NA | 118 (24.6) | 609 (39.4) | ||||
| Cell_Type (%) | 1 urothelial | 414 (86.4) | 1390 (90.0) | 0.090 | 0.111 | |
| 5 UC with variants (Squamous cell, glandular, sarcomatous, micro papillary, neuroendocrine, lymphoepithelial) | 61 (12.7) | 147 ( 9.5) | ||||
| 6 others | 4 ( 0.8) | 8 ( 0.5) | ||||
| 左右側 (%) | 1 左 | 249 (52.0) | 802 (51.9) | 0.990 | 0.008 | |
| 2 右 | 223 (46.6) | 719 (46.5) | ||||
| 3 雙側 | 7 ( 1.5) | 24 ( 1.6) | ||||
| 腫瘤位置 (%) | 0 non-visible | 1 ( 0.2) | 1 ( 0.1) | 0.517 | 0.104 | |
| 1 腎盂 | 186 (38.8) | 655 (42.4) | ||||
| 2 輸尿管 | 175 (36.5) | 500 (32.4) | ||||
| 3 膀胱袖口 | 1 ( 0.2) | 2 ( 0.1) | ||||
| 4 多個位置 | 115 (24.0) | 385 (24.9) | ||||
| 5 無法識別 | 1 ( 0.2) | 2 ( 0.1) | ||||
| 多發性 (%) | 0 Not available | 19 ( 4.0) | 92 ( 6.0) | 0.246 | 0.092 | |
| 1 No | 295 (61.6) | 936 (60.6) | ||||
| 2 Yes | 165 (34.4) | 517 (33.5) | ||||
| 腫瘤大小 (%) | 0 Not available | 7 ( 1.5) | 56 ( 3.6) | 0.050 | 0.141 | |
| 1 <2cm | 153 (31.9) | 462 (29.9) | ||||
| 2 >=2cm | 319 (66.6) | 1027 (66.5) | ||||
| 病理分期 (%) | 1 stage 0a/0is | 73 (15.2) | 241 (15.6) | 0.018 | 0.185 | |
| 2 stage I | 118 (24.6) | 436 (28.2) | ||||
| 3 stage II | 79 (16.5) | 296 (19.2) | ||||
| 4 stage III | 144 (30.1) | 442 (28.6) | ||||
| 5 stage IV | 52 (10.9) | 106 ( 6.9) | ||||
| NA | 13 ( 2.7) | 24 ( 1.6) | ||||
| 完整檢體腫瘤惡性度 (%) | 1 papillary urothelial neoplasm of low malignant potential | 1 ( 0.2) | 1 ( 0.1) | 0.185 | 0.124 | |
| 2 low grade | 47 ( 9.8) | 140 ( 9.1) | ||||
| 3 high grade | 418 (87.3) | 1372 (88.8) | ||||
| 4 Gx | 2 ( 0.4) | 15 ( 1.0) | ||||
| NA | 11 ( 2.3) | 17 ( 1.1) | ||||
| 合併膀胱腫瘤 (%) | 0 No | 356 (74.3) | 1078 (69.8) | 0.096 | 0.159 | |
| 1 Previous Hx of bladder UC | 33 ( 6.9) | 114 ( 7.4) | ||||
| 2 Concurrent Bladder UC | 70 (14.6) | 261 (16.9) | ||||
| 3 Not available | 14 ( 2.9) | 41 ( 2.7) | ||||
| NA | 6 ( 1.3) | 51 ( 3.3) | ||||
| 合併CIS (%) | 0 No | 323 (67.4) | 1060 (68.6) | 0.062 | 0.133 | |
| 1 Yes | 149 (31.1) | 434 (28.1) | ||||
| NA | 7 ( 1.5) | 51 ( 3.3) | ||||
| Lymphovascular_invasion (%) | 0 No | 366 (76.4) | 1256 (81.3) | <0.001 | 0.189 | |
| 1 Yes | 92 (19.2) | 267 (17.3) | ||||
| NA | 21 ( 4.4) | 22 ( 1.4) | ||||
| surgical_margin (%) | 0 free | 449 (93.7) | 1472 (95.3) | 0.066 | 0.117 | |
| 1 positive | 26 ( 5.4) | 51 ( 3.3) | ||||
| NA | 4 ( 0.8) | 22 ( 1.4) | ||||
| 術前水腎 (%) | 1 No | 207 (43.2) | 719 (46.5) | 0.137 | 0.106 | |
| 2 Yes | 258 (53.9) | 761 (49.3) | ||||
| NA | 14 ( 2.9) | 65 ( 4.2) | ||||
| Tumor_Necrosis (%) | 0 No | 412 (86.0) | 1133 (73.3) | <0.001 | 0.439 | |
| 1 Yes | 57 (11.9) | 208 (13.5) | ||||
| NA | 10 ( 2.1) | 204 (13.2) | ||||
| 有無針對UTUC化療 (%) | 0 No | 321 (67.0) | 1075 (69.6) | 0.018 | 0.155 | |
| 1 Yes | 148 (30.9) | 404 (26.1) | ||||
| 2 Not available | 10 ( 2.1) | 66 ( 4.3) | ||||
| 針對UTUC化療型態 (%) | 1 neo-adjuvant | 20 ( 4.2) | 42 ( 2.7) | 0.008 | 0.176 | |
| 2 adjuvant | 92 (19.2) | 297 (19.2) | ||||
| 3 salvage (curative intent) | 13 ( 2.7) | 15 ( 1.0) | ||||
| 4 palliative (S/S relieve) | 23 ( 4.8) | 52 ( 3.4) | ||||
| NA | 331 (69.1) | 1139 (73.7) | ||||
| 化療處方 (%) | 1 Gemcitabine & cisplatin | 39 ( 8.1) | 125 ( 8.1) | 0.079 | 0.151 | |
| 2 MVAC | 10 ( 2.1) | 11 ( 0.7) | ||||
| 3 Taxans-based | 0 ( 0.0) | 1 ( 0.1) | ||||
| 4 Carboplatin-based | 49 (10.2) | 141 ( 9.1) | ||||
| 5 others | 45 ( 9.4) | 117 ( 7.6) | ||||
| NA | 336 (70.1) | 1150 (74.4) | ||||
| Bladder_cuff_resection (%) | 0 Not perform BCR | 11 ( 2.3) | 47 ( 3.0) | <0.001 | 2.194 | |
| 1 Open incision | 92 (19.2) | 1027 (66.5) | ||||
| 2 Transurethral incision | 9 ( 1.9) | 55 ( 3.6) | ||||
| 4 Laparoscopy | 6 ( 1.3) | 306 (19.8) | ||||
| 5 Robot assisted | 321 (67.0) | 5 ( 0.3) | ||||
| NA | 40 ( 8.4) | 105 ( 6.8) | ||||
| simultaneously_ipsilateral_adrenalectomy (%) | 0 No | 408 (85.2) | 1205 (78.0) | 0.001 | 0.202 | |
| 1 Yes | 26 ( 5.4) | 95 ( 6.1) | ||||
| NA | 45 ( 9.4) | 245 (15.9) | ||||
| Post_operation_intravesical_CT_instillation (%) | 1 No | 356 (74.3) | 1370 (88.7) | <0.001 | 0.477 | |
| 2 術中膀胱灌藥 | 41 ( 8.6) | 6 ( 0.4) | ||||
| 3 術後膀胱灌藥 | 38 ( 7.9) | 51 ( 3.3) | ||||
| NA | 44 ( 9.2) | 118 ( 7.6) | ||||
| Clavien_Dindo_classification (%) | 0 No Complication | 284 (59.3) | 905 (58.6) | 0.011 | 0.243 | |
| 1 Grade I | 78 (16.3) | 175 (11.3) | ||||
| 2 Grade II | 76 (15.9) | 239 (15.5) | ||||
| 3 Grade IIIa | 4 ( 0.8) | 14 ( 0.9) | ||||
| 4 Grade IIIb | 4 ( 0.8) | 21 ( 1.4) | ||||
| 5 Grade IVa | 3 ( 0.6) | 16 ( 1.0) | ||||
| 6 Grade IVb | 0 ( 0.0) | 1 ( 0.1) | ||||
| 7 Grade V | 3 ( 0.6) | 6 ( 0.4) | ||||
| NA | 27 ( 5.6) | 168 (10.9) | ||||
| Disease_free (%) | 0 No | 107 (22.3) | 258 (16.7) | <0.001 | 0.238 | |
| 1 Yes | 317 (66.2) | 1089 (70.5) | ||||
| 3 Segmental resection 後復發或轉移 | 11 ( 2.3) | 6 ( 0.4) | ||||
| 4 Unknown | 44 ( 9.2) | 192 (12.4) | ||||
| Mortality (%) | 0 No | 313 (65.3) | 838 (54.2) | <0.001 | 0.343 | |
| 1 UTUC related | 66 (13.8) | 176 (11.4) | ||||
| 2 Non-UTUC related | 44 ( 9.2) | 232 (15.0) | ||||
| 3 死因不明 | 27 ( 5.6) | 204 (13.2) | ||||
| 4 Surgery related | 2 ( 0.4) | 9 ( 0.6) | ||||
| 5 無法判斷生死 | 27 ( 5.6) | 86 ( 5.6) | ||||
| 長期_Complication (%) | ESRD | 11 ( 2.3) | 48 ( 3.1) | 0.020 | 0.231 | |
| ESRD, ileus | 0 ( 0.0) | 3 ( 0.2) | ||||
| ESRD, ureter stricture (手術患側) | 0 ( 0.0) | 1 ( 0.1) | ||||
| ESRD, ventral hernia | 1 ( 0.2) | 1 ( 0.1) | ||||
| ileus | 6 ( 1.3) | 12 ( 0.8) | ||||
| ileus, ventral hernia | 0 ( 0.0) | 6 ( 0.4) | ||||
| No Complication | 426 (88.9) | 1362 (88.2) | ||||
| No Complication, ureter stricture (手術患側) | 0 ( 0.0) | 2 ( 0.1) | ||||
| ureter stricture (手術患側) | 13 ( 2.7) | 11 ( 0.7) | ||||
| ventral hernia | 4 ( 0.8) | 12 ( 0.8) | ||||
| NA | 18 ( 3.8) | 87 ( 5.6) | ||||
| Lost_follow_up (%) | 0 No | 419 (87.5) | 1386 (89.7) | 0.004 | 0.172 | |
| 1 Yes | 50 (10.4) | 100 ( 6.5) | ||||
| NA | 10 ( 2.1) | 59 ( 3.8) | ||||
| 術後住院天數_day (mean (SD)) | 7.60 (4.16) | 8.44 (5.67) | 0.004 | 0.168 | ||
| 手術到死亡間隔時間_月 (mean (SD)) | 24.10 (17.50) | 38.73 (32.69) | <0.001 | 0.558 | ||
| Longest_follow_up_month_for_BDFS_DFS (mean (SD)) | 31.35 (22.81) | 39.23 (31.63) | <0.001 | 0.286 | ||
| 診斷年紀 (mean (SD)) | 69.29 (10.23) | 68.74 (10.49) | 0.309 | 0.054 | ||
| 性別參數 (mean (SD)) | 0.58 (0.49) | 0.59 (0.49) | 0.757 | 0.016 | ||
| 術前eGFR_MDRD_ml_min_1_73m2 (mean (SD)) | 59.81 (44.62) | 55.12 (43.81) | 0.042 | 0.106 | ||
| Post_OP_1_month_eGFR (mean (SD)) | 161.97 (98.04) | 164.65 (97.89) | 0.601 | 0.027 |
NA| level | 1 ROBOT | 2 LPS+LESS | p | test | SMD | |
|---|---|---|---|---|---|---|
| n | 479 | 1545 | ||||
| ECOG (%) | 0 無症狀 | 248 (53.9) | 609 (49.1) | 0.235 | 0.138 | |
| 1 有症狀,可步行對生活不影響 | 187 (40.7) | 536 (43.2) | ||||
| 2 躺在床上時間小於50% | 22 ( 4.8) | 83 ( 6.7) | ||||
| 3 躺在床上時間大於50% | 3 ( 0.7) | 9 ( 0.7) | ||||
| 4 完全臥床 | 0 ( 0.0) | 4 ( 0.3) | ||||
| 性別 (%) | 1 男 | 202 (42.2) | 636 (41.2) | 0.736 | 0.020 | |
| 2 女 | 277 (57.8) | 909 (58.8) | ||||
| BMI (%) | Normal | 228 (63.2) | 582 (62.2) | 0.793 | 0.020 | |
| Overweight | 133 (36.8) | 354 (37.8) | ||||
| Cell_Type (%) | 1 urothelial | 414 (86.4) | 1390 (90.0) | 0.090 | 0.111 | |
| 5 UC with variants (Squamous cell, glandular, sarcomatous, micro papillary, neuroendocrine, lymphoepithelial) | 61 (12.7) | 147 ( 9.5) | ||||
| 6 others | 4 ( 0.8) | 8 ( 0.5) | ||||
| 左右側 (%) | 1 左 | 249 (52.0) | 802 (51.9) | 0.990 | 0.008 | |
| 2 右 | 223 (46.6) | 719 (46.5) | ||||
| 3 雙側 | 7 ( 1.5) | 24 ( 1.6) | ||||
| 腫瘤位置 (%) | 0 non-visible | 1 ( 0.2) | 1 ( 0.1) | 0.517 | 0.104 | |
| 1 腎盂 | 186 (38.8) | 655 (42.4) | ||||
| 2 輸尿管 | 175 (36.5) | 500 (32.4) | ||||
| 3 膀胱袖口 | 1 ( 0.2) | 2 ( 0.1) | ||||
| 4 多個位置 | 115 (24.0) | 385 (24.9) | ||||
| 5 無法識別 | 1 ( 0.2) | 2 ( 0.1) | ||||
| 多發性 (%) | 0 Not available | 19 ( 4.0) | 92 ( 6.0) | 0.246 | 0.092 | |
| 1 No | 295 (61.6) | 936 (60.6) | ||||
| 2 Yes | 165 (34.4) | 517 (33.5) | ||||
| 腫瘤大小 (%) | 0 Not available | 7 ( 1.5) | 56 ( 3.6) | 0.050 | 0.141 | |
| 1 <2cm | 153 (31.9) | 462 (29.9) | ||||
| 2 >=2cm | 319 (66.6) | 1027 (66.5) | ||||
| 病理分期 (%) | 1 stage 0a/0is | 73 (15.7) | 241 (15.8) | 0.028 | 0.168 | |
| 2 stage I | 118 (25.3) | 436 (28.7) | ||||
| 3 stage II | 79 (17.0) | 296 (19.5) | ||||
| 4 stage III | 144 (30.9) | 442 (29.1) | ||||
| 5 stage IV | 52 (11.2) | 106 ( 7.0) | ||||
| 完整檢體腫瘤惡性度 (%) | 1 papillary urothelial neoplasm of low malignant potential | 1 ( 0.2) | 1 ( 0.1) | 0.497 | 0.082 | |
| 2 low grade | 47 (10.0) | 140 ( 9.2) | ||||
| 3 high grade | 418 (89.3) | 1372 (89.8) | ||||
| 4 Gx | 2 ( 0.4) | 15 ( 1.0) | ||||
| 合併膀胱腫瘤 (%) | 0 No | 356 (75.3) | 1078 (72.2) | 0.519 | 0.081 | |
| 1 Previous Hx of bladder UC | 33 ( 7.0) | 114 ( 7.6) | ||||
| 2 Concurrent Bladder UC | 70 (14.8) | 261 (17.5) | ||||
| 3 Not available | 14 ( 3.0) | 41 ( 2.7) | ||||
| 合併CIS (%) | 0 No | 323 (68.4) | 1060 (71.0) | 0.324 | 0.055 | |
| 1 Yes | 149 (31.6) | 434 (29.0) | ||||
| Lymphovascular_invasion (%) | 0 No | 366 (79.9) | 1256 (82.5) | 0.240 | 0.065 | |
| 1 Yes | 92 (20.1) | 267 (17.5) | ||||
| surgical_margin (%) | 0 free | 449 (94.5) | 1472 (96.7) | 0.050 | 0.104 | |
| 1 positive | 26 ( 5.5) | 51 ( 3.3) | ||||
| 術前水腎 (%) | 1 No | 207 (44.5) | 719 (48.6) | 0.139 | 0.082 | |
| 2 Yes | 258 (55.5) | 761 (51.4) | ||||
| Tumor_Necrosis (%) | 0 No | 412 (87.8) | 1133 (84.5) | 0.090 | 0.097 | |
| 1 Yes | 57 (12.2) | 208 (15.5) | ||||
| 有無針對UTUC化療 (%) | 0 No | 321 (67.0) | 1075 (69.6) | 0.018 | 0.155 | |
| 1 Yes | 148 (30.9) | 404 (26.1) | ||||
| 2 Not available | 10 ( 2.1) | 66 ( 4.3) | ||||
| 針對UTUC化療型態 (%) | 1 neo-adjuvant | 20 (13.5) | 42 (10.3) | 0.029 | 0.273 | |
| 2 adjuvant | 92 (62.2) | 297 (73.2) | ||||
| 3 salvage (curative intent) | 13 ( 8.8) | 15 ( 3.7) | ||||
| 4 palliative (S/S relieve) | 23 (15.5) | 52 (12.8) | ||||
| 化療處方 (%) | 1 Gemcitabine & cisplatin | 39 (27.3) | 125 (31.6) | 0.202 | 0.224 | |
| 2 MVAC | 10 ( 7.0) | 11 ( 2.8) | ||||
| 3 Taxans-based | 0 ( 0.0) | 1 ( 0.3) | ||||
| 4 Carboplatin-based | 49 (34.3) | 141 (35.7) | ||||
| 5 others | 45 (31.5) | 117 (29.6) | ||||
| Bladder_cuff_resection (%) | 0 Not perform BCR | 11 ( 2.5) | 47 ( 3.3) | <0.001 | 2.391 | |
| 1 Open incision | 92 (21.0) | 1027 (71.3) | ||||
| 2 Transurethral incision | 9 ( 2.1) | 55 ( 3.8) | ||||
| 4 Laparoscopy | 6 ( 1.4) | 306 (21.2) | ||||
| 5 Robot assisted | 321 (73.1) | 5 ( 0.3) | ||||
| simultaneously_ipsilateral_adrenalectomy (%) | 0 No | 408 (94.0) | 1205 (92.7) | 0.410 | 0.053 | |
| 1 Yes | 26 ( 6.0) | 95 ( 7.3) | ||||
| Post_operation_intravesical_CT_instillation (%) | 1 No | 356 (81.8) | 1370 (96.0) | <0.001 | 0.495 | |
| 2 術中膀胱灌藥 | 41 ( 9.4) | 6 ( 0.4) | ||||
| 3 術後膀胱灌藥 | 38 ( 8.7) | 51 ( 3.6) | ||||
| Clavien_Dindo_classification (%) | 0 No Complication | 284 (62.8) | 905 (65.7) | 0.318 | 0.155 | |
| 1 Grade I | 78 (17.3) | 175 (12.7) | ||||
| 2 Grade II | 76 (16.8) | 239 (17.4) | ||||
| 3 Grade IIIa | 4 ( 0.9) | 14 ( 1.0) | ||||
| 4 Grade IIIb | 4 ( 0.9) | 21 ( 1.5) | ||||
| 5 Grade IVa | 3 ( 0.7) | 16 ( 1.2) | ||||
| 6 Grade IVb | 0 ( 0.0) | 1 ( 0.1) | ||||
| 7 Grade V | 3 ( 0.7) | 6 ( 0.4) | ||||
| Disease_free (%) | 0 No | 107 (22.3) | 258 (16.7) | <0.001 | 0.238 | |
| 1 Yes | 317 (66.2) | 1089 (70.5) | ||||
| 3 Segmental resection 後復發或轉移 | 11 ( 2.3) | 6 ( 0.4) | ||||
| 4 Unknown | 44 ( 9.2) | 192 (12.4) | ||||
| Mortality (%) | 0 No | 313 (65.3) | 838 (54.2) | <0.001 | 0.343 | |
| 1 UTUC related | 66 (13.8) | 176 (11.4) | ||||
| 2 Non-UTUC related | 44 ( 9.2) | 232 (15.0) | ||||
| 3 死因不明 | 27 ( 5.6) | 204 (13.2) | ||||
| 4 Surgery related | 2 ( 0.4) | 9 ( 0.6) | ||||
| 5 無法判斷生死 | 27 ( 5.6) | 86 ( 5.6) | ||||
| 長期_Complication (%) | ESRD | 11 ( 2.4) | 48 ( 3.3) | 0.032 | 0.218 | |
| ESRD, ileus | 0 ( 0.0) | 3 ( 0.2) | ||||
| ESRD, ureter stricture (手術患側) | 0 ( 0.0) | 1 ( 0.1) | ||||
| ESRD, ventral hernia | 1 ( 0.2) | 1 ( 0.1) | ||||
| ileus | 6 ( 1.3) | 12 ( 0.8) | ||||
| ileus, ventral hernia | 0 ( 0.0) | 6 ( 0.4) | ||||
| No Complication | 426 (92.4) | 1362 (93.4) | ||||
| No Complication, ureter stricture (手術患側) | 0 ( 0.0) | 2 ( 0.1) | ||||
| ureter stricture (手術患側) | 13 ( 2.8) | 11 ( 0.8) | ||||
| ventral hernia | 4 ( 0.9) | 12 ( 0.8) | ||||
| Lost_follow_up (%) | 0 No | 419 (89.3) | 1386 (93.3) | 0.007 | 0.140 | |
| 1 Yes | 50 (10.7) | 100 ( 6.7) | ||||
| 術後住院天數_day (mean (SD)) | 7.60 (4.16) | 8.44 (5.67) | 0.004 | 0.168 | ||
| 手術到死亡間隔時間_月 (mean (SD)) | 24.10 (17.50) | 38.73 (32.69) | <0.001 | 0.558 | ||
| Longest_follow_up_month_for_BDFS_DFS (mean (SD)) | 31.35 (22.81) | 39.23 (31.63) | <0.001 | 0.286 | ||
| 診斷年紀 (mean (SD)) | 69.29 (10.23) | 68.74 (10.49) | 0.309 | 0.054 | ||
| 性別參數 (mean (SD)) | 0.58 (0.49) | 0.59 (0.49) | 0.757 | 0.016 | ||
| 術前eGFR_MDRD_ml_min_1_73m2 (mean (SD)) | 59.81 (44.62) | 55.12 (43.81) | 0.042 | 0.106 | ||
| Post_OP_1_month_eGFR (mean (SD)) | 161.97 (98.04) | 164.65 (97.89) | 0.601 | 0.027 |
| level | 1 ROBOT | 2 LPS+LESS | p | test | SMD | |
|---|---|---|---|---|---|---|
| n | 482 | 1551 | ||||
| ECOG (%) | 0 無症狀 | 251 (52.1) | 612 (39.5) | <0.001 | 0.522 | |
| 1 有症狀,可步行對生活不影響 | 187 (38.8) | 538 (34.7) | ||||
| 2 躺在床上時間小於50% | 22 ( 4.6) | 83 ( 5.4) | ||||
| 3 躺在床上時間大於50% | 3 ( 0.6) | 9 ( 0.6) | ||||
| 4 完全臥床 | 0 ( 0.0) | 4 ( 0.3) | ||||
| NA | 19 ( 3.9) | 305 (19.7) | ||||
| 性別 (%) | 1 男 | 203 (42.1) | 636 (41.0) | 0.704 | 0.023 | |
| 2 女 | 279 (57.9) | 915 (59.0) | ||||
| 身高 (mean (SD)) | 158.38 (8.36) | 158.01 (8.49) | 0.480 | 0.044 | ||
| 體重 (mean (SD)) | 60.72 (11.61) | 61.42 (22.53) | 0.576 | 0.039 | ||
| Cell_Type (%) | 1 urothelial | 414 (85.9) | 1393 (89.8) | 0.038 | 0.156 | |
| 2 squamous | 0 ( 0.0) | 2 ( 0.1) | ||||
| 3 small cell | 2 ( 0.4) | 1 ( 0.1) | ||||
| 4 adenocarcinoma | 1 ( 0.2) | 0 ( 0.0) | ||||
| 5 UC with variants (Squamous cell, glandular, sarcomatous, micro papillary, neuroendocrine, lymphoepithelial) | 61 (12.7) | 147 ( 9.5) | ||||
| 6 others | 4 ( 0.8) | 8 ( 0.5) | ||||
| 左右側 (%) | 1 左 | 251 (52.1) | 805 (51.9) | 0.953 | 0.037 | |
| 2 右 | 224 (46.5) | 721 (46.5) | ||||
| 3 雙側 | 7 ( 1.5) | 24 ( 1.5) | ||||
| NA | 0 ( 0.0) | 1 ( 0.1) | ||||
| 腫瘤位置_多選 (%) | 0 non-visible | 1 ( 0.2) | 2 ( 0.1) | 0.191 | 0.348 | |
| 1 腎盂 | 187 (38.8) | 656 (42.3) | ||||
| 1 腎盂, 2 上輸尿管 | 42 ( 8.7) | 136 ( 8.8) | ||||
| 1 腎盂, 2 上輸尿管, 4 下輸尿管 | 0 ( 0.0) | 9 ( 0.6) | ||||
| 1 腎盂, 2 上輸尿管, 4 下輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 2 ( 0.1) | ||||
| 1 腎盂, 2 上輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 2 ( 0.1) | ||||
| 1 腎盂, 4 下輸尿管 | 14 ( 2.9) | 40 ( 2.6) | ||||
| 1 腎盂, 4 下輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 1 ( 0.1) | ||||
| 1 腎盂, 5 膀胱袖口 | 0 ( 0.0) | 2 ( 0.1) | ||||
| 1 腎盂, 5 膀胱袖口, 6 Urerter, unknown site | 1 ( 0.2) | 0 ( 0.0) | ||||
| 1 腎盂, 6 Urerter, unknown site | 10 ( 2.1) | 12 ( 0.8) | ||||
| 2 上輸尿管 | 70 (14.5) | 166 (10.7) | ||||
| 2 上輸尿管, 4 下輸尿管 | 3 ( 0.6) | 10 ( 0.6) | ||||
| 2 上輸尿管, 4 下輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 1 ( 0.1) | ||||
| 2 上輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 2 ( 0.1) | ||||
| 2 上輸尿管, 6 Urerter, unknown site | 0 ( 0.0) | 1 ( 0.1) | ||||
| 3 中輸尿管 | 46 ( 9.5) | 136 ( 8.8) | ||||
| 3 中輸尿管, 1 腎盂 | 5 ( 1.0) | 28 ( 1.8) | ||||
| 3 中輸尿管, 1 腎盂, 2 上輸尿管 | 6 ( 1.2) | 14 ( 0.9) | ||||
| 3 中輸尿管, 1 腎盂, 2 上輸尿管, 4 下輸尿管 | 5 ( 1.0) | 20 ( 1.3) | ||||
| 3 中輸尿管, 1 腎盂, 2 上輸尿管, 4 下輸尿管, 5 膀胱袖口 | 2 ( 0.4) | 1 ( 0.1) | ||||
| 3 中輸尿管, 1 腎盂, 4 下輸尿管 | 6 ( 1.2) | 12 ( 0.8) | ||||
| 3 中輸尿管, 1 腎盂, 4 下輸尿管, 5 膀胱袖口 | 1 ( 0.2) | 0 ( 0.0) | ||||
| 3 中輸尿管, 1 腎盂, 5 膀胱袖口 | 0 ( 0.0) | 3 ( 0.2) | ||||
| 3 中輸尿管, 2 上輸尿管 | 9 ( 1.9) | 23 ( 1.5) | ||||
| 3 中輸尿管, 2 上輸尿管, 4 下輸尿管 | 0 ( 0.0) | 19 ( 1.2) | ||||
| 3 中輸尿管, 2 上輸尿管, 4 下輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 1 ( 0.1) | ||||
| 3 中輸尿管, 4 下輸尿管 | 7 ( 1.5) | 31 ( 2.0) | ||||
| 3 中輸尿管, 4 下輸尿管, 5 膀胱袖口 | 1 ( 0.2) | 1 ( 0.1) | ||||
| 3 中輸尿管, 5 膀胱袖口 | 0 ( 0.0) | 4 ( 0.3) | ||||
| 4 下輸尿管 | 56 (11.6) | 187 (12.1) | ||||
| 4 下輸尿管, 5 膀胱袖口 | 3 ( 0.6) | 11 ( 0.7) | ||||
| 5 膀胱袖口 | 1 ( 0.2) | 2 ( 0.1) | ||||
| 6 Urerter, unknown site | 5 ( 1.0) | 14 ( 0.9) | ||||
| 7 Not available | 1 ( 0.2) | 1 ( 0.1) | ||||
| NA | 0 ( 0.0) | 1 ( 0.1) | ||||
| 多發性 (%) | 0 Not available | 10 ( 2.1) | 30 ( 1.9) | 0.174 | 0.127 | |
| 1 No | 298 (61.8) | 939 (60.5) | ||||
| 2 Yes | 165 (34.2) | 520 (33.5) | ||||
| NA | 9 ( 1.9) | 62 ( 4.0) | ||||
| 腫瘤大小 (%) | 0 non-visible | 6 ( 1.2) | 24 ( 1.5) | 0.030 | 0.233 | |
| 1 <1cm | 26 ( 5.4) | 49 ( 3.2) | ||||
| 1 <1cm | 13 ( 2.7) | 74 ( 4.8) | ||||
| 2 ≥1 & < 2 cm | 40 ( 8.3) | 134 ( 8.6) | ||||
| 2 ≥1 & < 2 cm | 68 (14.1) | 182 (11.7) | ||||
| 3 ≥2 & < 3 cm | 40 ( 8.3) | 152 ( 9.8) | ||||
| 3 ≥2 & < 3 cm | 77 (16.0) | 215 (13.9) | ||||
| 4 ≥ 3cm | 205 (42.5) | 665 (42.9) | ||||
| Not available | 4 ( 0.8) | 39 ( 2.5) | ||||
| NA | 3 ( 0.6) | 17 ( 1.1) | ||||
| 病理分期 (%) | 1 stage 0a | 68 (14.1) | 210 (13.5) | 0.015 | 0.203 | |
| 2 stage 0is | 5 ( 1.0) | 31 ( 2.0) | ||||
| 3 stage I | 118 (24.5) | 438 (28.2) | ||||
| 4 stage II | 79 (16.4) | 296 (19.1) | ||||
| 5 stage III | 146 (30.3) | 444 (28.6) | ||||
| 6 stage IV | 53 (11.0) | 107 ( 6.9) | ||||
| NA | 13 ( 2.7) | 25 ( 1.6) | ||||
| 完整檢體腫瘤惡性度 (%) | 1 papillary urothelial neoplasm of low malignant potential | 1 ( 0.2) | 1 ( 0.1) | <0.001 | 0.325 | |
| 2 low grade | 47 ( 9.8) | 140 ( 9.0) | ||||
| 3 high grade | 416 (86.3) | 1290 (83.2) | ||||
| 4 Gx | 4 ( 0.8) | 15 ( 1.0) | ||||
| 6 G2 | 2 ( 0.4) | 86 ( 5.5) | ||||
| 8 Well differentiated | 0 ( 0.0) | 1 ( 0.1) | ||||
| NA | 12 ( 2.5) | 18 ( 1.2) | ||||
| 合併膀胱腫瘤 (%) | 0 No | 359 (74.5) | 1083 (69.8) | 0.088 | 0.161 | |
| 1 Previous Hx of bladder UC | 33 ( 6.8) | 114 ( 7.4) | ||||
| 2 Concurrent Bladder UC | 70 (14.5) | 262 (16.9) | ||||
| 3 Not available | 14 ( 2.9) | 41 ( 2.6) | ||||
| NA | 6 ( 1.2) | 51 ( 3.3) | ||||
| 合併CIS (%) | 0 No | 326 (67.6) | 1064 (68.6) | 0.058 | 0.134 | |
| 1 Yes | 149 (30.9) | 435 (28.0) | ||||
| NA | 7 ( 1.5) | 52 ( 3.4) | ||||
| Lymphovascular_invasion (%) | 0 No | 368 (76.3) | 1261 (81.3) | <0.001 | 0.196 | |
| 1 Yes | 92 (19.1) | 268 (17.3) | ||||
| NA | 22 ( 4.6) | 22 ( 1.4) | ||||
| surgical_margin (%) | 0 free | 451 (93.6) | 1475 (95.1) | 0.044 | 0.126 | |
| 1 positive | 27 ( 5.6) | 52 ( 3.4) | ||||
| NA | 4 ( 0.8) | 24 ( 1.5) | ||||
| 術前水腎 (%) | 1 No | 208 (43.2) | 722 (46.6) | 0.129 | 0.107 | |
| 2 Yes | 260 (53.9) | 764 (49.3) | ||||
| NA | 14 ( 2.9) | 65 ( 4.2) | ||||
| Tumor_Necrosis (%) | 0 No | 414 (85.9) | 1138 (73.4) | <0.001 | 0.439 | |
| 1 Yes | 58 (12.0) | 208 (13.4) | ||||
| NA | 10 ( 2.1) | 205 (13.2) | ||||
| 有無針對UTUC化療 (%) | 0 No | 322 (66.8) | 1078 (69.5) | 0.028 | 0.172 | |
| 1 Yes | 150 (31.1) | 407 (26.2) | ||||
| 2 Not available | 0 ( 0.0) | 8 ( 0.5) | ||||
| NA | 10 ( 2.1) | 58 ( 3.7) | ||||
| 針對UTUC化療型態 (%) | 1 neo-adjuvant | 20 ( 4.1) | 42 ( 2.7) | 0.008 | 0.176 | |
| 2 adjuvant | 94 (19.5) | 299 (19.3) | ||||
| 3 salvage (curative intent) | 13 ( 2.7) | 15 ( 1.0) | ||||
| 4 palliative (S/S relieve) | 23 ( 4.8) | 52 ( 3.4) | ||||
| NA | 332 (68.9) | 1143 (73.7) | ||||
| 化療處方 (%) | 1 Gemcitabine & cisplatin | 39 ( 8.1) | 125 ( 8.1) | 0.066 | 0.154 | |
| 2 MVAC | 10 ( 2.1) | 11 ( 0.7) | ||||
| 3 Taxans-based | 0 ( 0.0) | 1 ( 0.1) | ||||
| 4 Carboplatin-based | 49 (10.2) | 141 ( 9.1) | ||||
| 5 others | 47 ( 9.8) | 119 ( 7.7) | ||||
| NA | 337 (69.9) | 1154 (74.4) | ||||
| Bladder_cuff_resection (%) | 0 Not perform BCR | 11 ( 2.3) | 47 ( 3.0) | <0.001 | 2.177 | |
| 1 Open incision | 94 (19.5) | 1030 (66.4) | ||||
| 2 Transurethral incision | 9 ( 1.9) | 56 ( 3.6) | ||||
| 4 Laparoscopy | 6 ( 1.2) | 302 (19.5) | ||||
| 5 Robot assisted | 321 (66.6) | 5 ( 0.3) | ||||
| 6 LESS | 0 ( 0.0) | 5 ( 0.3) | ||||
| NA | 41 ( 8.5) | 106 ( 6.8) | ||||
| simultaneously_ipsilateral_adrenalectomy (%) | 0 no | 410 (85.1) | 1210 (78.0) | 0.002 | 0.197 | |
| 1 yes | 26 ( 5.4) | 95 ( 6.1) | ||||
| NA | 46 ( 9.5) | 246 (15.9) | ||||
| Post_operation_intravesical_CT_instillation (%) | 1 No | 356 (73.9) | 1367 (88.1) | <0.001 | 0.496 | |
| 1 No, 7 術中膀胱灌藥-Mitomycin C | 1 ( 0.2) | 0 ( 0.0) | ||||
| 10 Yes, Epirubicin | 3 ( 0.6) | 8 ( 0.5) | ||||
| 2 Yes, Mitomycin C | 18 ( 3.7) | 35 ( 2.3) | ||||
| 3 Yes, Doxorubicin | 19 ( 3.9) | 13 ( 0.8) | ||||
| 3 Yes, Doxorubicin, 6 Yes, Cisplatin | 0 ( 0.0) | 1 ( 0.1) | ||||
| 5 Yes, BCG | 1 ( 0.2) | 2 ( 0.1) | ||||
| 5 Yes, BCG, 10 Yes, Epirubicin | 0 ( 0.0) | 1 ( 0.1) | ||||
| 7 術中膀胱灌藥-Mitomycin C | 10 ( 2.1) | 2 ( 0.1) | ||||
| 8 術中膀胱灌藥-Epirubicin | 30 ( 6.2) | 3 ( 0.2) | ||||
| 9 術中膀胱灌藥-Gemcitabine | 0 ( 0.0) | 1 ( 0.1) | ||||
| NA | 44 ( 9.1) | 118 ( 7.6) | ||||
| Clavien_Dindo_classification_複選 (%) | 0 No Complication | 285 (59.1) | 910 (58.7) | 0.115 | 0.289 | |
| 1 Grade I: | 79 (16.4) | 175 (11.3) | ||||
| 1 Grade I:, 2 Grade II: | 11 ( 2.3) | 20 ( 1.3) | ||||
| 1 Grade I:, 2 Grade II:, 4 - IIIb | 0 ( 0.0) | 1 ( 0.1) | ||||
| 1 Grade I:, 2 Grade II:, 4 - IIIb, 5 Grade - IVa, 7 Greade V | 1 ( 0.2) | 0 ( 0.0) | ||||
| 1 Grade I:, 2 Grade II:, 5 Grade - IVa | 0 ( 0.0) | 1 ( 0.1) | ||||
| 1 Grade I:, 2 Grade II:, 7 Greade V | 0 ( 0.0) | 2 ( 0.1) | ||||
| 1 Grade I:, 4 - IIIb | 0 ( 0.0) | 1 ( 0.1) | ||||
| 1 Grade I:, 4 - IIIb, 6 - IVb, 7 Greade V | 0 ( 0.0) | 1 ( 0.1) | ||||
| 1 Grade I:, 5 Grade - IVa | 0 ( 0.0) | 1 ( 0.1) | ||||
| 2 Grade II: | 65 (13.5) | 219 (14.1) | ||||
| 2 Grade II:, 3 Grade - IIIa: | 1 ( 0.2) | 5 ( 0.3) | ||||
| 2 Grade II:, 4 - IIIb | 1 ( 0.2) | 5 ( 0.3) | ||||
| 2 Grade II:, 4 - IIIb, 3 Grade - IIIa: | 0 ( 0.0) | 1 ( 0.1) | ||||
| 2 Grade II:, 4 - IIIb, 7 Greade V, 3 Grade - IIIa: | 0 ( 0.0) | 1 ( 0.1) | ||||
| 2 Grade II:, 5 Grade - IVa | 1 ( 0.2) | 4 ( 0.3) | ||||
| 2 Grade II:, 6 - IVb, 7 Greade V, 3 Grade - IIIa: | 0 ( 0.0) | 1 ( 0.1) | ||||
| 2 Grade II:, 7 Greade V | 1 ( 0.2) | 0 ( 0.0) | ||||
| 3 Grade - IIIa: | 3 ( 0.6) | 10 ( 0.6) | ||||
| 4 - IIIb | 3 ( 0.6) | 13 ( 0.8) | ||||
| 5 Grade - IVa | 2 ( 0.4) | 10 ( 0.6) | ||||
| 6 - IVb | 0 ( 0.0) | 1 ( 0.1) | ||||
| 6 - IVb, 7 Greade V | 1 ( 0.2) | 1 ( 0.1) | ||||
| NA | 28 ( 5.8) | 168 (10.8) | ||||
| Disease_free (%) | 0 No (NxUx) | 1 ( 0.2) | 3 ( 0.2) | <0.001 | 0.262 | |
| 0 NUx 後復發或轉移 | 106 (22.0) | 255 (16.4) | ||||
| 1 Yes | 6 ( 1.2) | 31 ( 2.0) | ||||
| 1 Yes，沒有復發或轉移 | 313 (64.9) | 1063 (68.5) | ||||
| 3 Segmental resection 後復發或轉移 | 12 ( 2.5) | 7 ( 0.5) | ||||
| 4 Unknown | 0 ( 0.0) | 3 ( 0.2) | ||||
| 4 不知道 | 35 ( 7.3) | 132 ( 8.5) | ||||
| NA | 9 ( 1.9) | 57 ( 3.7) | ||||
| Mortality (%) | 0 no | 315 (65.4) | 843 (54.4) | <0.001 | 0.408 | |
| 1 UTUC related | 67 (13.9) | 176 (11.3) | ||||
| 2 non-UTUC related | 44 ( 9.1) | 232 (15.0) | ||||
| 3 Nonknown | 18 ( 3.7) | 179 (11.5) | ||||
| 3 死因不明 | 9 ( 1.9) | 26 ( 1.7) | ||||
| 4 Surgery related | 2 ( 0.4) | 9 ( 0.6) | ||||
| 5 無法判斷生死 | 18 ( 3.7) | 28 ( 1.8) | ||||
| NA | 9 ( 1.9) | 58 ( 3.7) | ||||
| 長期_Complication (%) | ESRD | 11 ( 2.3) | 48 ( 3.1) | 0.020 | 0.231 | |
| ESRD, ileus | 0 ( 0.0) | 3 ( 0.2) | ||||
| ESRD, ureter stricture (手術患側) | 0 ( 0.0) | 1 ( 0.1) | ||||
| ESRD, ventral hernia | 1 ( 0.2) | 1 ( 0.1) | ||||
| ileus | 6 ( 1.2) | 12 ( 0.8) | ||||
| ileus, ventral hernia | 0 ( 0.0) | 6 ( 0.4) | ||||
| No Complication | 429 (89.0) | 1368 (88.2) | ||||
| No Complication, ureter stricture (手術患側) | 0 ( 0.0) | 2 ( 0.1) | ||||
| ureter stricture (手術患側) | 13 ( 2.7) | 11 ( 0.7) | ||||
| ventral hernia | 4 ( 0.8) | 12 ( 0.8) | ||||
| NA | 18 ( 3.7) | 87 ( 5.6) | ||||
| Lost_follow_up (%) | 0 No | 422 (87.6) | 1392 (89.7) | 0.004 | 0.171 | |
| 1 Yes | 50 (10.4) | 100 ( 6.4) | ||||
| NA | 10 ( 2.1) | 59 ( 3.8) | ||||
| 術後住院天數_day (mean (SD)) | 7.59 (4.15) | 8.43 (5.66) | 0.004 | 0.169 | ||
| 手術到死亡間隔時間_月 (mean (SD)) | 23.98 (17.47) | 40691.78 (824169.30) | 0.585 | 0.070 | ||
| Longest_follow_up_month_for_BDFS_DFS (mean (SD)) | 31.50 (22.99) | 39.26 (31.61) | <0.001 | 0.281 | ||
| 診斷年紀 (mean (SD)) | 69.33 (10.23) | 68.71 (10.50) | 0.253 | 0.060 | ||
| 性別參數 (mean (SD)) | 0.58 (0.49) | 0.59 (0.49) | 0.725 | 0.018 | ||
| 術前eGFR_MDRD_ml_min_1_73m2 (mean (SD)) | Inf (NaN) | Inf (NaN) | NaN | NaN | ||
| Post_OP_1_month_eGFR (mean (SD)) | Inf (NaN) | Inf (NaN) | NaN | NaN |
missingValue.Table(RobotLPS2)matrixplot_missing(RobotLPS2)